A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53. [electronic resource]
Producer: 20150303Description: 910-7 p. digitalISSN:- 1872-7980
- Animals
- Apoptosis
- Blotting, Western
- Bone Neoplasms -- metabolism
- Chromatin Immunoprecipitation
- Flow Cytometry
- Humans
- Immunoprecipitation
- Intracellular Signaling Peptides and Proteins -- genetics
- Mice
- Mice, Nude
- Osteosarcoma -- metabolism
- Peptide Fragments -- genetics
- Repressor Proteins -- genetics
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53 -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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