A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53.
Qiu, Shi
A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53. [electronic resource] - Cancer letters Jan 2015 - 910-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-7980
10.1016/j.canlet.2014.10.044 doi
Animals
Apoptosis
Blotting, Western
Bone Neoplasms--metabolism
Chromatin Immunoprecipitation
Flow Cytometry
Humans
Immunoprecipitation
Intracellular Signaling Peptides and Proteins--genetics
Mice
Mice, Nude
Osteosarcoma--metabolism
Peptide Fragments--genetics
Repressor Proteins--genetics
Tumor Cells, Cultured
Tumor Suppressor Protein p53--genetics
Xenograft Model Antitumor Assays
A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53. [electronic resource] - Cancer letters Jan 2015 - 910-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-7980
10.1016/j.canlet.2014.10.044 doi
Animals
Apoptosis
Blotting, Western
Bone Neoplasms--metabolism
Chromatin Immunoprecipitation
Flow Cytometry
Humans
Immunoprecipitation
Intracellular Signaling Peptides and Proteins--genetics
Mice
Mice, Nude
Osteosarcoma--metabolism
Peptide Fragments--genetics
Repressor Proteins--genetics
Tumor Cells, Cultured
Tumor Suppressor Protein p53--genetics
Xenograft Model Antitumor Assays