Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors. [electronic resource]
Producer: 20151109Description: 315-331 p. digitalISSN:- 1768-3254
- Apoptosis Regulatory Proteins -- metabolism
- Binding Sites -- drug effects
- Dose-Response Relationship, Drug
- Drug Design
- Humans
- Molecular Structure
- Myeloid Cell Leukemia Sequence 1 Protein -- antagonists & inhibitors
- Pyrroles -- chemical synthesis
- Structure-Activity Relationship
- bcl-X Protein -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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