Peptidylarginine deiminase inhibition impairs Toll-like receptor agonist-induced functional maturation of dendritic cells, resulting in the loss of T cell-proliferative capacity: a partial mechanism with therapeutic potential in inflammatory settings. [electronic resource]
Producer: 20150324Description: 351-62 p. digitalISSN:- 1938-3673
- Animals
- B7-1 Antigen -- immunology
- CD4-Positive T-Lymphocytes -- immunology
- CD8-Positive T-Lymphocytes -- immunology
- Cell Proliferation -- drug effects
- Cytokines -- immunology
- Dendritic Cells -- immunology
- Female
- Hydrolases -- antagonists & inhibitors
- Inflammation -- chemically induced
- Lipopolysaccharides -- toxicity
- MAP Kinase Signaling System -- drug effects
- Mice
- NF-kappa B -- pharmacology
- Ornithine -- analogs & derivatives
- Protein-Arginine Deiminases
- Toll-Like Receptors -- agonists
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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