Down-regulation of miRNA-106b inhibits growth of melanoma cells by promoting G1-phase cell cycle arrest and reactivation of p21/WAF1/Cip1 protein. [electronic resource]
Producer: 20150831Description: 10636-49 p. digitalISSN:- 1949-2553
- Animals
- Apoptosis
- Blotting, Western
- Cell Cycle
- Cell Proliferation
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- Down-Regulation
- Female
- Flow Cytometry
- G1 Phase Cell Cycle Checkpoints
- Grape Seed Extract -- pharmacology
- Humans
- Immunoenzyme Techniques
- In Situ Hybridization, Fluorescence
- Melanoma -- drug therapy
- Mice
- Mice, Nude
- MicroRNAs -- genetics
- Proanthocyanidins -- pharmacology
- RNA, Messenger -- genetics
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53 -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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