Down-regulation of miRNA-106b inhibits growth of melanoma cells by promoting G1-phase cell cycle arrest and reactivation of p21/WAF1/Cip1 protein.
Prasad, Ram
Down-regulation of miRNA-106b inhibits growth of melanoma cells by promoting G1-phase cell cycle arrest and reactivation of p21/WAF1/Cip1 protein. [electronic resource] - Oncotarget Nov 2014 - 10636-49 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1949-2553
10.18632/oncotarget.2527 doi
Animals
Apoptosis
Blotting, Western
Cell Cycle
Cell Proliferation
Cyclin-Dependent Kinase Inhibitor p21--genetics
Down-Regulation
Female
Flow Cytometry
G1 Phase Cell Cycle Checkpoints
Grape Seed Extract--pharmacology
Humans
Immunoenzyme Techniques
In Situ Hybridization, Fluorescence
Melanoma--drug therapy
Mice
Mice, Nude
MicroRNAs--genetics
Proanthocyanidins--pharmacology
RNA, Messenger--genetics
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
Tumor Cells, Cultured
Tumor Suppressor Protein p53--genetics
Xenograft Model Antitumor Assays
Down-regulation of miRNA-106b inhibits growth of melanoma cells by promoting G1-phase cell cycle arrest and reactivation of p21/WAF1/Cip1 protein. [electronic resource] - Oncotarget Nov 2014 - 10636-49 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1949-2553
10.18632/oncotarget.2527 doi
Animals
Apoptosis
Blotting, Western
Cell Cycle
Cell Proliferation
Cyclin-Dependent Kinase Inhibitor p21--genetics
Down-Regulation
Female
Flow Cytometry
G1 Phase Cell Cycle Checkpoints
Grape Seed Extract--pharmacology
Humans
Immunoenzyme Techniques
In Situ Hybridization, Fluorescence
Melanoma--drug therapy
Mice
Mice, Nude
MicroRNAs--genetics
Proanthocyanidins--pharmacology
RNA, Messenger--genetics
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
Tumor Cells, Cultured
Tumor Suppressor Protein p53--genetics
Xenograft Model Antitumor Assays