Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells. [electronic resource]
Producer: 20150930Description: 31-42 p. digitalISSN:- 1573-6768
- Acrylamides -- pharmacology
- Benzamides -- pharmacology
- Cell Line
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Cellular Senescence -- drug effects
- Cytokines -- antagonists & inhibitors
- Dose-Response Relationship, Drug
- Fibroblasts -- cytology
- Glucose -- pharmacology
- Humans
- NAD -- metabolism
- Naphthols -- pharmacology
- Niacinamide -- metabolism
- Nicotinamide Phosphoribosyltransferase -- antagonists & inhibitors
- Piperidines -- pharmacology
- Sirtuin 1 -- antagonists & inhibitors
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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