Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence. [electronic resource]
Producer: 20160202Description: 4706 p. digitalISSN:- 2041-1723
- Adaptor Proteins, Signal Transducing -- genetics
- Androstadienes -- pharmacology
- Apoptosis Regulatory Proteins -- genetics
- Autophagy -- drug effects
- Beclin-1
- Cells, Cultured
- Cellular Senescence -- physiology
- Cycloheximide -- pharmacology
- Fibroblasts -- drug effects
- Gene Knockdown Techniques
- Humans
- Membrane Proteins -- genetics
- Microtubule-Associated Proteins -- genetics
- Protein Isoforms -- metabolism
- RNA, Small Interfering
- Sequestosome-1 Protein
- Tumor Suppressor Protein p53 -- genetics
- Ubiquitin-Protein Ligases -- genetics
- Wortmannin
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Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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