A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding. [electronic resource]
Producer: 20150526Description: 983-90 p. digitalISSN:- 2211-1247
- Animals
- Base Sequence
- CDX2 Transcription Factor
- Cell Line, Tumor
- Colonic Neoplasms -- genetics
- Enhancer Elements, Genetic
- Gene Expression Regulation, Neoplastic
- Genetic Association Studies
- Genetic Predisposition to Disease
- Homeodomain Proteins -- metabolism
- Humans
- Intercellular Signaling Peptides and Proteins -- genetics
- Mice, Transgenic
- Organ Specificity
- Polymorphism, Single Nucleotide
- Risk
- Transcription Factor 7-Like 2 Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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