Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects. [electronic resource]
Producer: 20150824Description: 767-82 p. digitalISSN:- 2211-1247
- Animals
- Bone Marrow -- metabolism
- Core Binding Factor Alpha 2 Subunit -- genetics
- Core Binding Factor Alpha 3 Subunit -- genetics
- DNA Repair
- Fanconi Anemia -- genetics
- Fanconi Anemia Complementation Group D2 Protein -- metabolism
- Gene Deletion
- Genetic Predisposition to Disease
- HCT116 Cells
- HEK293 Cells
- HeLa Cells
- Humans
- Leukemia -- genetics
- Mice
- Mice, Inbred C57BL
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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