FK506-loaded chitosan conduit promotes the regeneration of injured sciatic nerves in the rat through the upregulation of brain-derived neurotrophic factor and TrkB. [electronic resource]
Producer: 20150511Description: 20-6 p. digitalISSN:- 1878-5883
- Animals
- Biocompatible Materials -- therapeutic use
- Brain-Derived Neurotrophic Factor -- metabolism
- Chitosan -- therapeutic use
- Disease Models, Animal
- Drug Combinations
- Electric Stimulation
- Evoked Potentials -- drug effects
- GAP-43 Protein -- metabolism
- Immunosuppressive Agents -- therapeutic use
- Male
- Nerve Regeneration -- drug effects
- Neural Conduction -- drug effects
- Rats
- Rats, Wistar
- Receptor, trkB -- genetics
- Sciatic Neuropathy -- drug therapy
- Tacrolimus -- therapeutic use
- Time Factors
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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