FK506-loaded chitosan conduit promotes the regeneration of injured sciatic nerves in the rat through the upregulation of brain-derived neurotrophic factor and TrkB.
Zhao, Jia
FK506-loaded chitosan conduit promotes the regeneration of injured sciatic nerves in the rat through the upregulation of brain-derived neurotrophic factor and TrkB. [electronic resource] - Journal of the neurological sciences Sep 2014 - 20-6 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1878-5883
10.1016/j.jns.2014.06.005 doi
Animals
Biocompatible Materials--therapeutic use
Brain-Derived Neurotrophic Factor--metabolism
Chitosan--therapeutic use
Disease Models, Animal
Drug Combinations
Electric Stimulation
Evoked Potentials--drug effects
GAP-43 Protein--metabolism
Immunosuppressive Agents--therapeutic use
Male
Nerve Regeneration--drug effects
Neural Conduction--drug effects
Rats
Rats, Wistar
Receptor, trkB--genetics
Sciatic Neuropathy--drug therapy
Tacrolimus--therapeutic use
Time Factors
Up-Regulation--drug effects
FK506-loaded chitosan conduit promotes the regeneration of injured sciatic nerves in the rat through the upregulation of brain-derived neurotrophic factor and TrkB. [electronic resource] - Journal of the neurological sciences Sep 2014 - 20-6 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1878-5883
10.1016/j.jns.2014.06.005 doi
Animals
Biocompatible Materials--therapeutic use
Brain-Derived Neurotrophic Factor--metabolism
Chitosan--therapeutic use
Disease Models, Animal
Drug Combinations
Electric Stimulation
Evoked Potentials--drug effects
GAP-43 Protein--metabolism
Immunosuppressive Agents--therapeutic use
Male
Nerve Regeneration--drug effects
Neural Conduction--drug effects
Rats
Rats, Wistar
Receptor, trkB--genetics
Sciatic Neuropathy--drug therapy
Tacrolimus--therapeutic use
Time Factors
Up-Regulation--drug effects