Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis. [electronic resource]
Producer: 20140820Description: 8149-54 p. digitalISSN:- 1091-6490
- Animals
- Brain Neoplasms -- immunology
- Carcinogenesis -- genetics
- Cell Proliferation
- Chickens
- Cyclin-Dependent Kinase Inhibitor p16 -- genetics
- Disease Models, Animal
- Gene Expression Regulation, Neoplastic -- physiology
- Genes, Tumor Suppressor -- physiology
- Glioblastoma -- immunology
- Heterozygote
- Humans
- Mice
- Mice, Knockout
- Neoplasm Transplantation
- Receptor-Like Protein Tyrosine Phosphatases, Class 2 -- genetics
- STAT3 Transcription Factor -- metabolism
- Tumor Microenvironment -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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