Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis.
Ortiz, Berenice
Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jun 2014 - 8149-54 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1091-6490
10.1073/pnas.1401952111 doi
Animals
Brain Neoplasms--immunology
Carcinogenesis--genetics
Cell Proliferation
Chickens
Cyclin-Dependent Kinase Inhibitor p16--genetics
Disease Models, Animal
Gene Expression Regulation, Neoplastic--physiology
Genes, Tumor Suppressor--physiology
Glioblastoma--immunology
Heterozygote
Humans
Mice
Mice, Knockout
Neoplasm Transplantation
Receptor-Like Protein Tyrosine Phosphatases, Class 2--genetics
STAT3 Transcription Factor--metabolism
Tumor Microenvironment--immunology
Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jun 2014 - 8149-54 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1091-6490
10.1073/pnas.1401952111 doi
Animals
Brain Neoplasms--immunology
Carcinogenesis--genetics
Cell Proliferation
Chickens
Cyclin-Dependent Kinase Inhibitor p16--genetics
Disease Models, Animal
Gene Expression Regulation, Neoplastic--physiology
Genes, Tumor Suppressor--physiology
Glioblastoma--immunology
Heterozygote
Humans
Mice
Mice, Knockout
Neoplasm Transplantation
Receptor-Like Protein Tyrosine Phosphatases, Class 2--genetics
STAT3 Transcription Factor--metabolism
Tumor Microenvironment--immunology