Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma. [electronic resource]
Producer: 20150219Description: 2688-702 p. digitalISSN:- 1949-2553
- Amino Acid Sequence
- Anaplastic Lymphoma Kinase
- Animals
- Base Sequence
- Biomarkers, Tumor -- genetics
- Blotting, Southern
- Blotting, Western
- Cell Transformation, Neoplastic -- genetics
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- Humans
- Immunoenzyme Techniques
- Integrases
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Molecular Sequence Data
- Mutation -- genetics
- N-Myc Proto-Oncogene Protein
- Neuroblastoma -- genetics
- Neurogenesis
- Oligonucleotide Array Sequence Analysis
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-ret -- genetics
- RNA, Messenger -- genetics
- Real-Time Polymerase Chain Reaction
- Receptor Protein-Tyrosine Kinases -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Sequence Homology, Amino Acid
- Transcriptional Activation
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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