The combination of the prodrugs perforin-CEBPD and perforin-granzyme B efficiently enhances the activation of caspase signaling and kills prostate cancer. [electronic resource]
Producer: 20141021Description: e1220 p. digitalISSN:- 2041-4889
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- BALB 3T3 Cells
- Binding Sites
- CCAAT-Enhancer-Binding Protein-delta -- pharmacology
- Caspase 3 -- metabolism
- Caspase 8 -- genetics
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- E2F1 Transcription Factor -- genetics
- Enhancer of Zeste Homolog 2 Protein
- Enzyme Activation
- Gene Expression Regulation, Neoplastic
- Genes, Reporter
- Granzymes -- pharmacology
- Humans
- Male
- Mice
- Neoplasm Proteins
- Perforin -- pharmacology
- Polycomb Repressive Complex 2 -- genetics
- Prodrugs -- metabolism
- Promoter Regions, Genetic
- Prostatic Neoplasms -- enzymology
- Receptors, Androgen -- drug effects
- Recombinant Fusion Proteins -- pharmacology
- Signal Transduction -- drug effects
- Time Factors
- Transcription Factors
- Transfection
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.