Cytotoxicity and antitumor activity of bis(platinum) complexes. A novel class of platinum complexes active in cell lines resistant to both cisplatin and 1,2-diaminocyclohexane complexes. [electronic resource]
Producer: 19900830Description: 2179-84 p. digitalISSN:- 0022-2623
- Animals
- Antineoplastic Agents -- pharmacology
- Cell Survival -- drug effects
- Cisplatin
- Cyclohexylamines
- DNA -- biosynthesis
- Drug Resistance
- Leukemia L1210 -- drug therapy
- Leukemia P388 -- drug therapy
- Magnetic Resonance Spectroscopy
- Molecular Conformation
- Molecular Structure
- Organoplatinum Compounds -- pharmacology
- Structure-Activity Relationship
- Tumor Cells, Cultured
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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