Cytotoxicity and antitumor activity of bis(platinum) complexes. A novel class of platinum complexes active in cell lines resistant to both cisplatin and 1,2-diaminocyclohexane complexes.
Farrell, N
Cytotoxicity and antitumor activity of bis(platinum) complexes. A novel class of platinum complexes active in cell lines resistant to both cisplatin and 1,2-diaminocyclohexane complexes. [electronic resource] - Journal of medicinal chemistry Aug 1990 - 2179-84 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-2623
10.1021/jm00170a021 doi
Animals
Antineoplastic Agents--pharmacology
Cell Survival--drug effects
Cisplatin
Cyclohexylamines
DNA--biosynthesis
Drug Resistance
Leukemia L1210--drug therapy
Leukemia P388--drug therapy
Magnetic Resonance Spectroscopy
Molecular Conformation
Molecular Structure
Organoplatinum Compounds--pharmacology
Structure-Activity Relationship
Tumor Cells, Cultured
Cytotoxicity and antitumor activity of bis(platinum) complexes. A novel class of platinum complexes active in cell lines resistant to both cisplatin and 1,2-diaminocyclohexane complexes. [electronic resource] - Journal of medicinal chemistry Aug 1990 - 2179-84 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-2623
10.1021/jm00170a021 doi
Animals
Antineoplastic Agents--pharmacology
Cell Survival--drug effects
Cisplatin
Cyclohexylamines
DNA--biosynthesis
Drug Resistance
Leukemia L1210--drug therapy
Leukemia P388--drug therapy
Magnetic Resonance Spectroscopy
Molecular Conformation
Molecular Structure
Organoplatinum Compounds--pharmacology
Structure-Activity Relationship
Tumor Cells, Cultured