[Relationship between warfarin dosing and activity of CYP2C9 assessed by the content of losartan and its metabolite E-3174 in the urine of patients with mechanical prosthetic heart valves]. [electronic resource]
Producer: 20140723Description: 21-4 p. digitalISSN:- 0022-9040
- Adult
- Anticoagulants -- pharmacokinetics
- Aryl Hydrocarbon Hydroxylases -- genetics
- Biotransformation -- genetics
- Cardiovascular Agents -- pharmacokinetics
- Cytochrome P-450 CYP2C9
- Dose-Response Relationship, Drug
- Drug Monitoring -- methods
- Female
- Genotype
- Heart Valve Diseases -- drug therapy
- Heart Valve Prosthesis Implantation -- methods
- Humans
- Imidazoles -- pharmacokinetics
- Losartan -- pharmacokinetics
- Male
- Middle Aged
- Pharmacogenetics
- Polymorphism, Genetic
- Postoperative Period
- Tetrazoles -- pharmacokinetics
- Warfarin -- pharmacokinetics
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Publication Type: Journal Article
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