[Relationship between warfarin dosing and activity of CYP2C9 assessed by the content of losartan and its metabolite E-3174 in the urine of patients with mechanical prosthetic heart valves].

Arslanbekova, S M

[Relationship between warfarin dosing and activity of CYP2C9 assessed by the content of losartan and its metabolite E-3174 in the urine of patients with mechanical prosthetic heart valves]. [electronic resource] - Kardiologiia 2013 - 21-4 p. digital

Publication Type: Journal Article

0022-9040


Adult
Anticoagulants--pharmacokinetics
Aryl Hydrocarbon Hydroxylases--genetics
Biotransformation--genetics
Cardiovascular Agents--pharmacokinetics
Cytochrome P-450 CYP2C9
Dose-Response Relationship, Drug
Drug Monitoring--methods
Female
Genotype
Heart Valve Diseases--drug therapy
Heart Valve Prosthesis Implantation--methods
Humans
Imidazoles--pharmacokinetics
Losartan--pharmacokinetics
Male
Middle Aged
Pharmacogenetics
Polymorphism, Genetic
Postoperative Period
Tetrazoles--pharmacokinetics
Warfarin--pharmacokinetics