Anti-neoplastic activity of low-dose endothelial-monocyte activating polypeptide-II results from defective autophagy and G2/M arrest mediated by PI3K/Akt/FoxO1 axis in human glioblastoma stem cells. [electronic resource]
Producer: 20140729Description: 477-89 p. digitalISSN:- 1873-2968
- Animals
- Antineoplastic Agents -- antagonists & inhibitors
- Autophagy -- drug effects
- Brain Neoplasms -- drug therapy
- Cell Line, Tumor
- Cytokines -- antagonists & inhibitors
- Forkhead Box Protein O1
- Forkhead Transcription Factors -- agonists
- G2 Phase -- drug effects
- Glioblastoma -- drug therapy
- Humans
- Male
- Mice
- Mice, Nude
- Neoplasm Proteins -- agonists
- Neoplastic Stem Cells -- drug effects
- Nerve Tissue Proteins -- agonists
- Neurons -- drug effects
- Phosphatidylinositol 3-Kinase -- chemistry
- RNA Interference
- RNA-Binding Proteins -- antagonists & inhibitors
- Random Allocation
- Recombinant Proteins -- pharmacology
- Second Messenger Systems -- drug effects
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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