p38α MAPK-mediated induction and interaction of FOXO3a and p53 contribute to the inhibited-growth and induced-apoptosis of human lung adenocarcinoma cells by berberine. [electronic resource]
Producer: 20140826Description: 36 p. digitalISSN:- 1756-9966
- Adenocarcinoma
- Adenocarcinoma of Lung
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Berberine -- pharmacology
- Cell Line, Tumor
- Cell Proliferation
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- Forkhead Box Protein O3
- Forkhead Transcription Factors -- genetics
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Gene Expression
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Lung Neoplasms
- MAP Kinase Signaling System
- Mitogen-Activated Protein Kinase 14 -- physiology
- Phosphorylation
- Protein Processing, Post-Translational
- Transcriptional Activation
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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