The canonical wnt signal restricts the glycogen synthase kinase 3/fbw7-dependent ubiquitination and degradation of eya1 phosphatase. [electronic resource]
Producer: 20140731Description: 2409-17 p. digitalISSN:- 1098-5549
- Animals
- Branchio-Oto-Renal Syndrome -- genetics
- Cell Line
- Cell Transformation, Neoplastic -- genetics
- Enzyme Activation
- F-Box Proteins -- antagonists & inhibitors
- F-Box-WD Repeat-Containing Protein 7
- Glycogen Synthase Kinase 3 -- antagonists & inhibitors
- HCT116 Cells
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- Mice
- Nuclear Proteins -- genetics
- Phosphatidylinositol 3-Kinase -- metabolism
- Protein Processing, Post-Translational
- Protein Tyrosine Phosphatases -- genetics
- Proto-Oncogene Proteins c-akt -- metabolism
- Ubiquitin
- Ubiquitin-Protein Ligases -- antagonists & inhibitors
- Ubiquitination
- Wnt Signaling Pathway -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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