The canonical wnt signal restricts the glycogen synthase kinase 3/fbw7-dependent ubiquitination and degradation of eya1 phosphatase.

Sun, Ye

The canonical wnt signal restricts the glycogen synthase kinase 3/fbw7-dependent ubiquitination and degradation of eya1 phosphatase. [electronic resource] - Molecular and cellular biology Jul 2014 - 2409-17 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1098-5549

10.1128/MCB.00104-14 doi


Animals
Branchio-Oto-Renal Syndrome--genetics
Cell Line
Cell Transformation, Neoplastic--genetics
Enzyme Activation
F-Box Proteins--antagonists & inhibitors
F-Box-WD Repeat-Containing Protein 7
Glycogen Synthase Kinase 3--antagonists & inhibitors
HCT116 Cells
Humans
Intracellular Signaling Peptides and Proteins--genetics
Mice
Nuclear Proteins--genetics
Phosphatidylinositol 3-Kinase--metabolism
Protein Processing, Post-Translational
Protein Tyrosine Phosphatases--genetics
Proto-Oncogene Proteins c-akt--metabolism
Ubiquitin
Ubiquitin-Protein Ligases--antagonists & inhibitors
Ubiquitination
Wnt Signaling Pathway--genetics