Second generation steroidal 4-aminoquinolines are potent, dual-target inhibitors of the botulinum neurotoxin serotype A metalloprotease and P. falciparum malaria. [electronic resource]
Producer: 20140808Description: 4134-53 p. digitalISSN:- 1520-4804
- Aminoquinolines -- chemical synthesis
- Animals
- Antimalarials -- chemical synthesis
- Botulinum Toxins, Type A -- antagonists & inhibitors
- Chick Embryo
- Chloroquine -- pharmacology
- Drug Resistance
- Hep G2 Cells
- Humans
- Metalloproteases -- drug effects
- Molecular Docking Simulation
- Plasmodium falciparum -- drug effects
- Protease Inhibitors -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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