Glucosamine-induced OGT activation mediates glucose production through cleaved Notch1 and FoxO1, which coordinately contributed to the regulation of maintenance of self-renewal in mouse embryonic stem cells. [electronic resource]
Producer: 20150422Description: 2067-79 p. digitalISSN:- 1557-8534
- Animals
- Cell Proliferation
- Cells, Cultured
- Embryonic Stem Cells -- physiology
- Forkhead Box Protein O1
- Forkhead Transcription Factors
- Gene Expression
- Gluconeogenesis
- Glucosamine -- physiology
- Glucose -- biosynthesis
- Glucose-6-Phosphatase -- metabolism
- Glycosylation
- Mice
- N-Acetylglucosaminyltransferases -- metabolism
- Phosphoenolpyruvate Carboxykinase (GTP) -- genetics
- Protein Processing, Post-Translational
- Proteolysis
- Reactive Oxygen Species -- metabolism
- Receptor, Notch1 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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