Glucosamine-induced OGT activation mediates glucose production through cleaved Notch1 and FoxO1, which coordinately contributed to the regulation of maintenance of self-renewal in mouse embryonic stem cells.
Jeon, Ji Hoon
Glucosamine-induced OGT activation mediates glucose production through cleaved Notch1 and FoxO1, which coordinately contributed to the regulation of maintenance of self-renewal in mouse embryonic stem cells. [electronic resource] - Stem cells and development Sep 2014 - 2067-79 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1557-8534
10.1089/scd.2013.0583 doi
Animals
Cell Proliferation
Cells, Cultured
Embryonic Stem Cells--physiology
Forkhead Box Protein O1
Forkhead Transcription Factors
Gene Expression
Gluconeogenesis
Glucosamine--physiology
Glucose--biosynthesis
Glucose-6-Phosphatase--metabolism
Glycosylation
Mice
N-Acetylglucosaminyltransferases--metabolism
Phosphoenolpyruvate Carboxykinase (GTP)--genetics
Protein Processing, Post-Translational
Proteolysis
Reactive Oxygen Species--metabolism
Receptor, Notch1--metabolism
Glucosamine-induced OGT activation mediates glucose production through cleaved Notch1 and FoxO1, which coordinately contributed to the regulation of maintenance of self-renewal in mouse embryonic stem cells. [electronic resource] - Stem cells and development Sep 2014 - 2067-79 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1557-8534
10.1089/scd.2013.0583 doi
Animals
Cell Proliferation
Cells, Cultured
Embryonic Stem Cells--physiology
Forkhead Box Protein O1
Forkhead Transcription Factors
Gene Expression
Gluconeogenesis
Glucosamine--physiology
Glucose--biosynthesis
Glucose-6-Phosphatase--metabolism
Glycosylation
Mice
N-Acetylglucosaminyltransferases--metabolism
Phosphoenolpyruvate Carboxykinase (GTP)--genetics
Protein Processing, Post-Translational
Proteolysis
Reactive Oxygen Species--metabolism
Receptor, Notch1--metabolism