Resistance to irinotecan (CPT-11) activates epidermal growth factor receptor/nuclear factor kappa B and increases cellular metastasis and autophagy in LoVo colon cancer cells. [electronic resource]
Producer: 20140828Description: 51-60 p. digitalISSN:- 1872-7980
- Autophagy -- drug effects
- Camptothecin -- analogs & derivatives
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Colonic Neoplasms -- drug therapy
- ErbB Receptors -- metabolism
- Humans
- I-kappa B Kinase -- metabolism
- Irinotecan
- NF-kappa B -- metabolism
- Neoplasm Metastasis
- Signal Transduction -- drug effects
- Topoisomerase I Inhibitors -- pharmacology
- Wnt Proteins -- metabolism
- beta Catenin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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