Resistance to irinotecan (CPT-11) activates epidermal growth factor receptor/nuclear factor kappa B and increases cellular metastasis and autophagy in LoVo colon cancer cells.
Chen, Ming-Cheng
Resistance to irinotecan (CPT-11) activates epidermal growth factor receptor/nuclear factor kappa B and increases cellular metastasis and autophagy in LoVo colon cancer cells. [electronic resource] - Cancer letters Jul 2014 - 51-60 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-7980
10.1016/j.canlet.2014.03.023 doi
Autophagy--drug effects
Camptothecin--analogs & derivatives
Cell Cycle--drug effects
Cell Line, Tumor
Colonic Neoplasms--drug therapy
ErbB Receptors--metabolism
Humans
I-kappa B Kinase--metabolism
Irinotecan
NF-kappa B--metabolism
Neoplasm Metastasis
Signal Transduction--drug effects
Topoisomerase I Inhibitors--pharmacology
Wnt Proteins--metabolism
beta Catenin--metabolism
Resistance to irinotecan (CPT-11) activates epidermal growth factor receptor/nuclear factor kappa B and increases cellular metastasis and autophagy in LoVo colon cancer cells. [electronic resource] - Cancer letters Jul 2014 - 51-60 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-7980
10.1016/j.canlet.2014.03.023 doi
Autophagy--drug effects
Camptothecin--analogs & derivatives
Cell Cycle--drug effects
Cell Line, Tumor
Colonic Neoplasms--drug therapy
ErbB Receptors--metabolism
Humans
I-kappa B Kinase--metabolism
Irinotecan
NF-kappa B--metabolism
Neoplasm Metastasis
Signal Transduction--drug effects
Topoisomerase I Inhibitors--pharmacology
Wnt Proteins--metabolism
beta Catenin--metabolism