Early axonal loss accompanied by impaired endocytosis, abnormal axonal transport, and decreased microtubule stability occur in the model of Krabbe's disease. [electronic resource]
Producer: 20140924Description: 92-103 p. digitalISSN:- 1095-953X
- Animals
- Axonal Transport -- physiology
- Axons -- pathology
- Cells, Cultured
- Disease Models, Animal
- Dyneins -- metabolism
- Endocytosis -- physiology
- Female
- Ganglia, Spinal -- pathology
- Leukodystrophy, Globoid Cell -- pathology
- Male
- Membrane Microdomains -- pathology
- Mice
- Mice, Neurologic Mutants
- Microtubules -- metabolism
- Motor Neurons -- pathology
- Neurites -- pathology
- Neurons -- pathology
- Sciatic Nerve -- injuries
- Synaptic Vesicles -- pathology
- Transport Vesicles -- pathology
- Tubulin -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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