Early axonal loss accompanied by impaired endocytosis, abnormal axonal transport, and decreased microtubule stability occur in the model of Krabbe's disease.

Teixeira, Carla Andreia

Early axonal loss accompanied by impaired endocytosis, abnormal axonal transport, and decreased microtubule stability occur in the model of Krabbe's disease. [electronic resource] - Neurobiology of disease Jun 2014 - 92-103 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1095-953X

10.1016/j.nbd.2014.02.012 doi


Animals
Axonal Transport--physiology
Axons--pathology
Cells, Cultured
Disease Models, Animal
Dyneins--metabolism
Endocytosis--physiology
Female
Ganglia, Spinal--pathology
Leukodystrophy, Globoid Cell--pathology
Male
Membrane Microdomains--pathology
Mice
Mice, Neurologic Mutants
Microtubules--metabolism
Motor Neurons--pathology
Neurites--pathology
Neurons--pathology
Sciatic Nerve--injuries
Synaptic Vesicles--pathology
Transport Vesicles--pathology
Tubulin--metabolism