Germline mutations in oncogene-induced senescence pathways are associated with multiple sessile serrated adenomas. [electronic resource]
Producer: 20140318Description: 520-9 p. digitalISSN:- 1528-0012
- Adaptor Proteins, Signal Transducing
- Adenomatous Polyps -- genetics
- Adult
- Aged
- Apoptosis Regulatory Proteins
- Ataxia Telangiectasia Mutated Proteins -- genetics
- Case-Control Studies
- Cellular Senescence -- genetics
- Codon, Nonsense
- Colonic Neoplasms -- genetics
- DNA Helicases -- genetics
- DNA-Binding Proteins -- genetics
- Exome
- Female
- Genetic Association Studies
- Genetic Markers
- Genetic Predisposition to Disease
- Genomics
- Germ-Line Mutation
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- Male
- Middle Aged
- Neoplasm Proteins -- genetics
- Oncogene Proteins -- genetics
- Precancerous Conditions -- genetics
- Prospective Studies
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins B-raf -- genetics
- Proto-Oncogene Proteins c-ets -- genetics
- Proto-Oncogene Proteins p21(ras)
- Retinoblastoma-Like Protein p107 -- genetics
- Sequence Analysis, DNA
- Ubiquitin-Protein Ligases
- ras Proteins -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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