Germline mutations in oncogene-induced senescence pathways are associated with multiple sessile serrated adenomas.

Gala, Manish K

Germline mutations in oncogene-induced senescence pathways are associated with multiple sessile serrated adenomas. [electronic resource] - Gastroenterology Feb 2014 - 520-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1528-0012

10.1053/j.gastro.2013.10.045 doi


Adaptor Proteins, Signal Transducing
Adenomatous Polyps--genetics
Adult
Aged
Apoptosis Regulatory Proteins
Ataxia Telangiectasia Mutated Proteins--genetics
Case-Control Studies
Cellular Senescence--genetics
Codon, Nonsense
Colonic Neoplasms--genetics
DNA Helicases--genetics
DNA-Binding Proteins--genetics
Exome
Female
Genetic Association Studies
Genetic Markers
Genetic Predisposition to Disease
Genomics
Germ-Line Mutation
Humans
Intracellular Signaling Peptides and Proteins--genetics
Male
Middle Aged
Neoplasm Proteins--genetics
Oncogene Proteins--genetics
Precancerous Conditions--genetics
Prospective Studies
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins B-raf--genetics
Proto-Oncogene Proteins c-ets--genetics
Proto-Oncogene Proteins p21(ras)
Retinoblastoma-Like Protein p107--genetics
Sequence Analysis, DNA
Ubiquitin-Protein Ligases
ras Proteins--genetics