Supplementation of ketoacids contributes to the up-regulation of the Wnt7a/Akt/p70S6K pathway and the down-regulation of apoptotic and ubiquitin-proteasome systems in the muscle of 5/6 nephrectomised rats. [electronic resource]
Producer: 20140602Description: 1536-48 p. digitalISSN:- 1475-2662
- Animals
- Apoptosis
- Diet, Protein-Restricted -- adverse effects
- Dietary Supplements
- Disease Models, Animal
- Down-Regulation
- Keto Acids -- therapeutic use
- Male
- Muscle Proteins -- biosynthesis
- Muscle, Skeletal -- metabolism
- Muscular Atrophy -- etiology
- Nephrectomy -- adverse effects
- Proteasome Endopeptidase Complex -- metabolism
- Proteolysis
- Proto-Oncogene Proteins -- agonists
- Random Allocation
- Rats
- Rats, Sprague-Dawley
- Renal Insufficiency, Chronic -- diet therapy
- Signal Transduction
- Ubiquitination
- Up-Regulation
- Wnt Proteins -- agonists
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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