Overexpression of ATP-activated P2X7 receptors in the intestinal mucosa is implicated in the pathogenesis of Crohn's disease. [electronic resource]
Producer: 20141017Description: 444-57 p. digitalISSN:- 1536-4844
- Adenosine Triphosphate -- metabolism
- Adolescent
- Adult
- Animals
- Apoptosis
- Blotting, Western
- Case-Control Studies
- Colitis, Ulcerative -- genetics
- Colonoscopy
- Crohn Disease -- genetics
- Enzyme-Linked Immunosorbent Assay
- Female
- Fluorescent Antibody Technique
- Follow-Up Studies
- Humans
- Interferon-gamma -- metabolism
- Interleukin-10 -- genetics
- Interleukin-1beta -- genetics
- Intestinal Mucosa -- metabolism
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Middle Aged
- Prognosis
- RNA, Messenger -- genetics
- Real-Time Polymerase Chain Reaction
- Receptors, Purinergic P2X7 -- physiology
- Reverse Transcriptase Polymerase Chain Reaction
- Tumor Necrosis Factor-alpha -- genetics
- Young Adult
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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