Intestine-specific deletion of SIRT1 in mice impairs DCoH2-HNF-1α-FXR signaling and alters systemic bile acid homeostasis. [electronic resource]
Producer: 20140515Description: 1006-16 p. digitalISSN:- 1528-0012
- Animals
- Bile Acids and Salts -- metabolism
- Cholesterol, Dietary -- metabolism
- Cholic Acid -- metabolism
- Feces -- chemistry
- Guanine Nucleotide Exchange Factors -- metabolism
- Hepatocyte Nuclear Factor 1-alpha -- metabolism
- Homeostasis
- Hydro-Lyases -- metabolism
- Ileum -- enzymology
- Intestinal Absorption
- Intestines -- enzymology
- Liver -- enzymology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Organic Anion Transporters, Sodium-Dependent -- metabolism
- Receptors, Cytoplasmic and Nuclear -- metabolism
- Rho Guanine Nucleotide Exchange Factors
- Signal Transduction
- Sirtuin 1 -- deficiency
- Symporters -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
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