Topoisomerase I inhibitor, camptothecin, induces apoptogenic signaling in human embryonic stem cells. [electronic resource]
Producer: 20150105Description: 400-14 p. digitalISSN:- 1876-7753
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Camptothecin -- pharmacology
- Cell Cycle -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- DNA Damage
- DNA Fragmentation
- Embryonic Stem Cells -- cytology
- Flow Cytometry
- Humans
- Mice
- Phosphorylation
- Signal Transduction -- drug effects
- Topoisomerase I Inhibitors -- pharmacology
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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