Topoisomerase I inhibitor, camptothecin, induces apoptogenic signaling in human embryonic stem cells.

García, Carolina Paola

Topoisomerase I inhibitor, camptothecin, induces apoptogenic signaling in human embryonic stem cells. [electronic resource] - Stem cell research Mar 2014 - 400-14 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1876-7753

10.1016/j.scr.2013.12.002 doi


Animals
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
Camptothecin--pharmacology
Cell Cycle--drug effects
Cell Survival--drug effects
Cells, Cultured
Cyclin-Dependent Kinase Inhibitor p21--metabolism
DNA Damage
DNA Fragmentation
Embryonic Stem Cells--cytology
Flow Cytometry
Humans
Mice
Phosphorylation
Signal Transduction--drug effects
Topoisomerase I Inhibitors--pharmacology
Tumor Suppressor Protein p53--metabolism