Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. [electronic resource]
Producer: 20140401Description: 429-40 p. digitalISSN:- 1521-0111
- AMP-Activated Protein Kinases -- genetics
- Animals
- Carrier Proteins -- genetics
- Cell Line
- Down-Regulation -- drug effects
- Doxorubicin -- pharmacology
- MAP Kinase Kinase Kinase 5 -- genetics
- Membrane Glycoproteins -- antagonists & inhibitors
- Mice
- Oxidative Stress -- drug effects
- Podocytes -- drug effects
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Small Molecule Libraries -- pharmacokinetics
- Thioredoxins -- genetics
- Toll-Like Receptor 7 -- antagonists & inhibitors
- Toll-Like Receptor 9 -- antagonists & inhibitors
- p38 Mitogen-Activated Protein Kinases -- genetics
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Publication Type: Journal Article
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