Establishment and characterization of bortezomib-resistant U266 cell line: constitutive activation of NF-κB-mediated cell signals and/or alterations of ubiquitylation-related genes reduce bortezomib-induced apoptosis. [electronic resource]
Producer: 20140826Description: 274-9 p. digitalISSN:- 1976-670X
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Boronic Acids -- pharmacology
- Bortezomib
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- genetics
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Multiple Myeloma -- drug therapy
- NF-kappa B -- metabolism
- Pyrazines -- pharmacology
- Signal Transduction -- drug effects
- Syndecan-1 -- metabolism
- Thalidomide -- pharmacology
- Ubiquitination
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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