Establishment and characterization of bortezomib-resistant U266 cell line: constitutive activation of NF-κB-mediated cell signals and/or alterations of ubiquitylation-related genes reduce bortezomib-induced apoptosis.
Park, Juwon
Establishment and characterization of bortezomib-resistant U266 cell line: constitutive activation of NF-κB-mediated cell signals and/or alterations of ubiquitylation-related genes reduce bortezomib-induced apoptosis. [electronic resource] - BMB reports May 2014 - 274-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1976-670X
10.5483/bmbrep.2014.47.5.134 doi
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Boronic Acids--pharmacology
Bortezomib
Cell Line, Tumor
Drug Resistance, Neoplasm--genetics
Gene Expression Regulation, Neoplastic--drug effects
Humans
Multiple Myeloma--drug therapy
NF-kappa B--metabolism
Pyrazines--pharmacology
Signal Transduction--drug effects
Syndecan-1--metabolism
Thalidomide--pharmacology
Ubiquitination
Establishment and characterization of bortezomib-resistant U266 cell line: constitutive activation of NF-κB-mediated cell signals and/or alterations of ubiquitylation-related genes reduce bortezomib-induced apoptosis. [electronic resource] - BMB reports May 2014 - 274-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1976-670X
10.5483/bmbrep.2014.47.5.134 doi
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Boronic Acids--pharmacology
Bortezomib
Cell Line, Tumor
Drug Resistance, Neoplasm--genetics
Gene Expression Regulation, Neoplastic--drug effects
Humans
Multiple Myeloma--drug therapy
NF-kappa B--metabolism
Pyrazines--pharmacology
Signal Transduction--drug effects
Syndecan-1--metabolism
Thalidomide--pharmacology
Ubiquitination