Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility. [electronic resource]
Producer: 20141013Description: 486-94 p. digitalISSN:- 1477-0539
- Acetyltransferases -- antagonists & inhibitors
- Adamantane -- chemical synthesis
- Aminobenzoates -- chemical synthesis
- Anilides -- chemical synthesis
- Dose-Response Relationship, Drug
- Drug Discovery
- Enzyme Inhibitors -- chemical synthesis
- Escherichia coli Proteins -- antagonists & inhibitors
- Fatty Acid Synthase, Type II -- antagonists & inhibitors
- Ligands
- Models, Molecular
- Molecular Conformation
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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