Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility.
Fisher, Martin
Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility. [electronic resource] - Organic & biomolecular chemistry Jan 2014 - 486-94 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1477-0539
10.1039/c3ob41975d doi
Acetyltransferases--antagonists & inhibitors
Adamantane--chemical synthesis
Aminobenzoates--chemical synthesis
Anilides--chemical synthesis
Dose-Response Relationship, Drug
Drug Discovery
Enzyme Inhibitors--chemical synthesis
Escherichia coli Proteins--antagonists & inhibitors
Fatty Acid Synthase, Type II--antagonists & inhibitors
Ligands
Models, Molecular
Molecular Conformation
Structure-Activity Relationship
Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility. [electronic resource] - Organic & biomolecular chemistry Jan 2014 - 486-94 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1477-0539
10.1039/c3ob41975d doi
Acetyltransferases--antagonists & inhibitors
Adamantane--chemical synthesis
Aminobenzoates--chemical synthesis
Anilides--chemical synthesis
Dose-Response Relationship, Drug
Drug Discovery
Enzyme Inhibitors--chemical synthesis
Escherichia coli Proteins--antagonists & inhibitors
Fatty Acid Synthase, Type II--antagonists & inhibitors
Ligands
Models, Molecular
Molecular Conformation
Structure-Activity Relationship