The Smad7-Skp2 complex orchestrates Myc stability, impacting on the cytostatic effect of TGF-β. [electronic resource]
Producer: 20141014Description: 411-21 p. digitalISSN:- 1477-9137
- Cell Line, Tumor
- Cytostatic Agents -- pharmacology
- Down-Regulation -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- HEK293 Cells
- Humans
- Inhibitor of Differentiation Proteins -- genetics
- Proteasome Endopeptidase Complex -- metabolism
- Protein Binding -- drug effects
- Protein Interaction Domains and Motifs
- Protein Interaction Mapping
- Protein Stability -- drug effects
- Proteolysis -- drug effects
- Proto-Oncogene Mas
- Proto-Oncogene Proteins c-myc -- metabolism
- S-Phase Kinase-Associated Proteins -- metabolism
- Smad7 Protein -- metabolism
- Transcription, Genetic -- drug effects
- Transforming Growth Factor beta -- pharmacology
- Ubiquitin -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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