The Smad7-Skp2 complex orchestrates Myc stability, impacting on the cytostatic effect of TGF-β.
Kim, Tae-Aug
The Smad7-Skp2 complex orchestrates Myc stability, impacting on the cytostatic effect of TGF-β. [electronic resource] - Journal of cell science Jan 2014 - 411-21 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
1477-9137
10.1242/jcs.136028 doi
Cell Line, Tumor
Cytostatic Agents--pharmacology
Down-Regulation--drug effects
Gene Expression Regulation, Neoplastic--drug effects
HEK293 Cells
Humans
Inhibitor of Differentiation Proteins--genetics
Proteasome Endopeptidase Complex--metabolism
Protein Binding--drug effects
Protein Interaction Domains and Motifs
Protein Interaction Mapping
Protein Stability--drug effects
Proteolysis--drug effects
Proto-Oncogene Mas
Proto-Oncogene Proteins c-myc--metabolism
S-Phase Kinase-Associated Proteins--metabolism
Smad7 Protein--metabolism
Transcription, Genetic--drug effects
Transforming Growth Factor beta--pharmacology
Ubiquitin--metabolism
The Smad7-Skp2 complex orchestrates Myc stability, impacting on the cytostatic effect of TGF-β. [electronic resource] - Journal of cell science Jan 2014 - 411-21 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
1477-9137
10.1242/jcs.136028 doi
Cell Line, Tumor
Cytostatic Agents--pharmacology
Down-Regulation--drug effects
Gene Expression Regulation, Neoplastic--drug effects
HEK293 Cells
Humans
Inhibitor of Differentiation Proteins--genetics
Proteasome Endopeptidase Complex--metabolism
Protein Binding--drug effects
Protein Interaction Domains and Motifs
Protein Interaction Mapping
Protein Stability--drug effects
Proteolysis--drug effects
Proto-Oncogene Mas
Proto-Oncogene Proteins c-myc--metabolism
S-Phase Kinase-Associated Proteins--metabolism
Smad7 Protein--metabolism
Transcription, Genetic--drug effects
Transforming Growth Factor beta--pharmacology
Ubiquitin--metabolism