Inhibitory studies of mexiletine and dextromethorphan oxidation in human liver microsomes. [electronic resource]
Producer: 19900502Description: 1045-53 p. digitalISSN:- 0006-2952
- Binding, Competitive
- Cytochrome P-450 CYP2D6
- Cytochrome P-450 Enzyme Inhibitors
- Dealkylation
- Dextromethorphan -- metabolism
- Drug Interactions
- Humans
- Hydroxylation
- Immune Sera -- pharmacology
- In Vitro Techniques
- Levorphanol -- analogs & derivatives
- Mexiletine -- metabolism
- Microsomes, Liver -- metabolism
- Mixed Function Oxygenases -- antagonists & inhibitors
- Oxidation-Reduction
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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