YB-1 disrupts mismatch repair complex formation, interferes with MutSα recruitment on mismatch and inhibits mismatch repair through interacting with PCNA. [electronic resource]
Producer: 20141222Description: 5065-77 p. digitalISSN:- 1476-5594
- Binding Sites
- DNA Mismatch Repair
- DNA-Binding Proteins -- metabolism
- Gene Expression Regulation, Neoplastic
- Gene Knockdown Techniques
- HeLa Cells
- Humans
- Methylnitronitrosoguanidine -- pharmacology
- Microsatellite Instability
- MutS Homolog 2 Protein -- metabolism
- Mutation
- Proliferating Cell Nuclear Antigen -- chemistry
- Protein Structure, Quaternary
- Protein Structure, Tertiary
- Y-Box-Binding Protein 1 -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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