TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection. [electronic resource]
Producer: 20140808Description: 91-101 p. digitalISSN:- 1365-2222
- Adult
- Asthma -- genetics
- Case-Control Studies
- DEAD Box Protein 58
- DEAD-box RNA Helicases -- genetics
- Epithelial Cells -- metabolism
- Female
- Gene Expression
- Gene Knockdown Techniques
- Humans
- Interferon Regulatory Factor-3 -- antagonists & inhibitors
- Interferon-Induced Helicase, IFIH1
- Interferons -- biosynthesis
- Interleukin-6 -- metabolism
- Interleukin-8 -- metabolism
- Male
- Middle Aged
- Picornaviridae Infections -- genetics
- Receptors, Immunologic
- Respiratory Mucosa -- immunology
- Rhinovirus -- immunology
- Signal Transduction
- Toll-Like Receptor 3 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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