TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection.

Parsons, K S

TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection. [electronic resource] - Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology Jan 2014 - 91-101 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1365-2222

10.1111/cea.12218 doi


Adult
Asthma--genetics
Case-Control Studies
DEAD Box Protein 58
DEAD-box RNA Helicases--genetics
Epithelial Cells--metabolism
Female
Gene Expression
Gene Knockdown Techniques
Humans
Interferon Regulatory Factor-3--antagonists & inhibitors
Interferon-Induced Helicase, IFIH1
Interferons--biosynthesis
Interleukin-6--metabolism
Interleukin-8--metabolism
Male
Middle Aged
Picornaviridae Infections--genetics
Receptors, Immunologic
Respiratory Mucosa--immunology
Rhinovirus--immunology
Signal Transduction
Toll-Like Receptor 3--genetics