Selective activation of cannabinoid receptor 2 in leukocytes suppresses their engagement of the brain endothelium and protects the blood-brain barrier. [electronic resource]
Producer: 20140610Description: 1548-1558 p. digitalISSN:- 1525-2191
- Actin Depolymerizing Factors -- metabolism
- Animals
- Blood-Brain Barrier -- metabolism
- Cell Adhesion
- Cell Adhesion Molecules -- metabolism
- Cell Line
- Cerebral Cortex -- blood supply
- Encephalitis -- metabolism
- Endothelial Cells -- metabolism
- Endothelium -- metabolism
- Humans
- Integrin alpha4beta1 -- chemistry
- Integrin beta1 -- metabolism
- Leukocytes -- metabolism
- Lipopolysaccharides
- Lymphocyte Function-Associated Antigen-1 -- chemistry
- Mice
- Microfilament Proteins -- metabolism
- Microvessels -- pathology
- Monocytes -- metabolism
- Phosphoproteins -- metabolism
- Phosphorylation
- Pseudopodia -- metabolism
- Receptor, Cannabinoid, CB2 -- agonists
- Transendothelial and Transepithelial Migration
- rac1 GTP-Binding Protein -- metabolism
- rhoA GTP-Binding Protein
- Vasodilator-Stimulated Phosphoprotein
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
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